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Search Results for " immune modulator "

20

Compounds

Cat No. Product Name Synonyms Targets
T0983 Penicillamine d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine Antibiotic
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...
T10696 CB2 modulator 1 Cannabinoid Receptor
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
T16792 Rovazolac ALX-101 Liver X Receptor
Rovazolac (ALX-101) is a liver x receptor (LXR) modulator used in the study of immune system disorders and atopic dermatitis.
T62204 NR2F6 modulator-1 Others
NR2F6 modulator-1 is a potent modulator of nuclear receptor subfamily 2, group F, member 6 (NR2F6). NR2F6 modulator-1 can be used to study immune regulation and modulation of tumour stem cell activity.
T34295 Resiniferatoxin RTX,[3H]resiniferatoxin IL Receptor
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response.
TN1879 Lucideric acid A Lucidenic acid A MMP , p38 MAPK , JNK
Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation.
T14046 Anandamide (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide Cannabinoid Receptor , Endogenous Metabolite
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...
T10824 Cis-Urocanic acid cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid 5-HT Receptor
cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
T72482 Dazostinag disodium STING
Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells.
T2539 Fingolimod hydrochloride Fingolimod (FTY720) HCl,FTY720 TRP/TRPV Channel , S1P Receptor , PAK , LPL Receptor
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
TN1420 Bacopaside I Others
Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...
T61025 GSK-1482160 P2X Receptor
GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so G...
T13182 Toll-like receptor modulator TLR
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
T12378L CA-170 PD-1-IN-1 Others
PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.
T12387 PD1-PDL1-IN 1 Others
PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.
TP1076 AUNP-12 NP-12
AUNP-12, a new immune checkpoint modulator, is an inhibitor of the PD-1 pathway.
T40355 IL-17A modulator-2
IL-17A modulator-2, exhibits inhibitory properties towards IL-17A, with a pIC50 of 8.3. Its effectiveness lies in attenuating the biological effects associated with IL-17A activity. IL-17A modulator-2 finds utility in th...
T72986 IMD-ferulic
IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.
T73630 PD1-PDL1-IN 1 TFA
PD1-PDL1-IN 1 TFA (compound 16) is a potent inhibitor of programmed cell death 1 (PD-1), functioning as an immune modulator [1].
T40354 IL-17A modulator-1
IL-17A modulator-1 is an effective inhibitor of IL-17A activity, exhibiting a pIC 50 value of 8.2. This compound holds great promise for studying diseases and disorders that involve the modulation of IL-17A, such as immu...
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