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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0983 | Penicillamine | d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine | Antibiotic |
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a... | |||
T10696 | CB2 modulator 1 | Cannabinoid Receptor | |
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia. | |||
T16792 | Rovazolac | ALX-101 | Liver X Receptor |
Rovazolac (ALX-101) is a liver x receptor (LXR) modulator used in the study of immune system disorders and atopic dermatitis. | |||
T62204 | NR2F6 modulator-1 | Others | |
NR2F6 modulator-1 is a potent modulator of nuclear receptor subfamily 2, group F, member 6 (NR2F6). NR2F6 modulator-1 can be used to study immune regulation and modulation of tumour stem cell activity. | |||
T34295 | Resiniferatoxin | RTX,[3H]resiniferatoxin | IL Receptor |
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response. | |||
TN1879 | Lucideric acid A | Lucidenic acid A | MMP , p38 MAPK , JNK |
Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation. | |||
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
T10824 | Cis-Urocanic acid | cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid | 5-HT Receptor |
cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor. | |||
T72482 | Dazostinag disodium | STING | |
Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells. | |||
T2539 | Fingolimod hydrochloride | Fingolimod (FTY720) HCl,FTY720 | TRP/TRPV Channel , S1P Receptor , PAK , LPL Receptor |
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells). | |||
TN1420 | Bacopaside I | Others | |
Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ... | |||
T61025 | GSK-1482160 | P2X Receptor | |
GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so G... | |||
T13182 | Toll-like receptor modulator | TLR | |
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function. | |||
T12378L | CA-170 | PD-1-IN-1 | Others |
PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator. | |||
T12387 | PD1-PDL1-IN 1 | Others | |
PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator. | |||
TP1076 | AUNP-12 | NP-12 | |
AUNP-12, a new immune checkpoint modulator, is an inhibitor of the PD-1 pathway. | |||
T40355 | IL-17A modulator-2 | ||
IL-17A modulator-2, exhibits inhibitory properties towards IL-17A, with a pIC50 of 8.3. Its effectiveness lies in attenuating the biological effects associated with IL-17A activity. IL-17A modulator-2 finds utility in th... | |||
T72986 | IMD-ferulic | ||
IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators. | |||
T73630 | PD1-PDL1-IN 1 TFA | ||
PD1-PDL1-IN 1 TFA (compound 16) is a potent inhibitor of programmed cell death 1 (PD-1), functioning as an immune modulator [1]. | |||
T40354 | IL-17A modulator-1 | ||
IL-17A modulator-1 is an effective inhibitor of IL-17A activity, exhibiting a pIC 50 value of 8.2. This compound holds great promise for studying diseases and disorders that involve the modulation of IL-17A, such as immu... |